Product: Asparaginase
Catalog Number: 17357
CAS Number: 9015-68-3
Synonyms: L-Asparagine Amidohydrolase
Pricing:
5 mg =  Inquire  
50 mg =  Inquire  
Formula: C1377H2208N382O442S17
Molecular Weight: 295.35
Appearance: Lyophilized powder
Category: Anti-cancer compounds
Stability: Stable under recommended storage conditions.
Storage:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8°C.

Transportation:

Non-hazardous for transport

Literature References:

Amy L. Swain, Mariusz Jaskolski, Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy Proc. Natl. Acad. Sci. U. S. A., 1993, 90:1474-1478.; Michel Duval, Stefan Suciu, Comparison of Escherichia coli–asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer—Children’s Leukemia Group phase 3 trial Blood, 2002, 99, 2734-2739.; Mario Sanches, Structural comparison of Escherichia coli L-asparaginase in two monoclinic space groups, Acta Crystallogr. D, 2003, 59(3):416.; Merck 14,836

Applications:

Asparaginase is an enzyme used in the treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma in children. It has minimal bone marrow toxicity.2