Product: Dolasetron Mesylate
Catalog Number: 17450
Synonyms: Dolasetron mesylate hydrate;
Dolasetron methanesulfonate hydrate
Pricing:
10 mg =  $200   Add to Cart
50 mg =  $550   Add to Cart
Formula: C19H20N2O3 • CH4O3S • xH2O
Chemical Purity: >98%
Molecular Weight: 420.48
Structure: Dolasetron Mesylate
Appearance: White powder
Category: Anti-cancer compounds
Stability: Stable under recommended storage conditions
Storage:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8°C

Transportation:

Non-hazardous for transport

Literature References:

Vergne-Salle, P., et al., A randomised, double-blind, placebo-controlled trial of dolasetron, a 5-hydroxytryptamine 3 receptor antagonist, in patients with fibromyalgia Eur. J. Pain, (2010); Mandanas, R.A., et al., A randomized, multicenter, open-label comparison of the antiemetic efficacy of dolasetron versus ondansetron for the prevention of nausea and vomiting during high-dose myeloablative chemotherapy Support. Cancer Ther. 2, 114-121, (2005); Kuryshev, Y.A., et al., Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels J. Pharmacol. Exp. Ther. 295, 614-620, (2000)

MSDS:
Description:

Dolasetron mesylate hydrate is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors.