Product: | Rifampicin | ||||
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Catalog Number: | 17858 | ||||
CAS Number: | 13292-46-1 | ||||
Synonyms: |
3-(4-Methylpiperazinyliminomethyl)rifamycin SV; Rifampin |
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Pricing: |
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Formula: | C43H58N4O12 | ||||
Molecular Weight: | 822.94 | ||||
Structure: | |||||
Appearance: | Red powder | ||||
Category: | Antibiotics | ||||
Stability: | Stable under recommended storage conditions. | ||||
Storage: |
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20¢ªC. Product is sensitive to light and moisture. Store under inert gas |
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Transportation: |
Non-hazardous for transport |
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Literature References: |
Wehrli, W., Rifampin: mechanisms of action and resistance. Rev. Infect. Dis. 5, S407-S411, (1983); Mustaev, A., Topology of the RNA polymerase active center probed by chimeric rifampicin-nucleotide compounds. Proc. Natl. Acad. Sci. U. S. A. 91, 12036, (1994); Wegrzyn, A., et al., Differential inhibition of transcription from sigma70- and sigma32-dependent promoters by rifampicin. FEBS Lett. 440, 172-174, (1998); Pfannschmidt, T., et al., The A and B forms of plastid DNA-dependent RNA polymerase from mustard (Sinapis alba L.) transcribe the same genes in a different developmental context. Mol. Gen. Genet. 257, 35-44, (1997); Sodeik, B., et al., Assembly of vaccinia virus: effects of rifampin on the intracellular distribution of viral protein p65. J. Virol. 68, 1103-1114, (1994); Tomiyama, T., et al., Rifampicin prevents the aggregation and neurotoxicity of amyloid beta protein in vitro. Biochem. Biophys. Res. Commun. 204, 76-83, (1994); Merck 14,8216 |
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MSDS: | |||||
Description: |
Inhibits the assembly of DNA and protein into mature virus particles |