Inquire About a Product| Product: | N-Desmethyl-4-hydroxy Tamoxifen (~1:1 E/Z Mixture) | ||||||||
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| Catalog Number: | 4935 | ||||||||
| CAS Number: | 110025-28-0 | ||||||||
| Synonyms: |
4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; (E/Z)-Endoxifen; 4OHNDtam |
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| Pricing: |
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| Formula: | C25H27NO2 | ||||||||
| Molecular Weight: | 373.49 | ||||||||
| Structure: |
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| Appearance: | Brown foam | ||||||||
| Category: | Unlabeled Reference Standards | ||||||||
| Stability: | Stable under recommended storage conditions. | ||||||||
| Storage: |
Store in a cool, dry place. |
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| Transportation: |
Non-hazardous for transport |
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| Literature References: |
Furr, B., et al.: Pharmacol. Ther., 25, 127 (1984), Leonessa, F., et al.: Cancer Res., 54, 441 (1994), Stearns, V., et al.: Lancet, 360, 1851 (2002), Rae, J., et al.: Pharmacogenetics, 13, 501 (2003) |
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| MSDS: | |||||||||
| Applications: |
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human |