Product: | Tacrolimus-13C,d2 | ||||
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Catalog Number: | C10249 | ||||
Unlabeled CAS Number: | 109581-93-3 | ||||
Notes: |
Ship at room temp. Storage -20 C. |
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Synonyms: | FK-506-13C,d2 | ||||
Pricing: |
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Formula: | C4313CH67D2NO12 | ||||
Molecular Weight: | 807.02 | ||||
Structure: | |||||
Category: | Labeled Reference Standards | ||||
Literature References: |
Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H., FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo), 1987, 40 (9): 1249–55.; M.M. Abou-Jaoude, R. Naim, J. Shaheen, N. Naufal, S. Abboud, M. AlHabash, M. Darwish, A. Mulhem, A. Ojjeh, and W.Y. Almawi, Tacrolimus (FK506) versus cyclosporin microemulsion (Neoral) as maintenance immunosuppresion therapy in kidney transplant recipients. Transplantation Proceedings, 2005, 37 (7): 3025–3028. |
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MSDS: | |||||
Applications: | A labeled immunosuppressant. Used after allogeneic organ transplants to reduce immune system activity and to lower the risk of organ rejection. Also used to treat atopic dermatitis, severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease. TH2-mediated diseases, and vitiligo. |